Since in a sentence

“I think,” said I, following as far as I could the methods of my companion, “that Dr. Mortimer is a successful, elderly medical man, well-esteemed since those who know him give him this mark of their appreciation.”
Arthur Conan Doyle, The Hound of Baskervilles

Since we have been so unfortunate as to miss him and have no notion of his errand, this accidental souvenir becomes of importance.
Arthur Conan Doyle, The Hound of Baskervilles

In my younger and more vulnerable years my father gave me some advice that I’ve been turning over in my mind ever since.
F. Scott Fitzgerald, The Great Gatsby

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Dictionary

Merriam-Webster
— from a definite past time until now
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Macmillan
— starting at a particular point in the past and continuing until now or until another point in the past
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Usage

12 uses of ‘since’ in The Great Gatsby, by F. Scott Fitzgerald
48 uses of ‘since’ in The Hound of the Baskervilles, by Arthur Conan Doyle